| Date | Location | Result | |
| 02/28/06 | West Chester PA - Hollinger Field House | West Chester 88, ESU 76 | Box score |
| 02/24/06 | East Stroudsburg PA - Koehler Fieldhouse | Kutztown 76, ESU 72 | Box score |
| 02/22/06 | Mansfield PA - Decker Gymnasium | Mansfield 96, ESU 91 | Box score |
| 02/18/06 | East Stroudsburg PA - Koehler Fieldhouse | West Chester 77, ESU 65 | Box score |
| 02/15/06 | Cheyney PA - Cope Hall | Cheyney 85, ESU 67 | Box score |
| 02/11/06 | East Stroudsburg PA - Koehler Fieldhouse | ESU 82, Millersville 71 | Box score |
| 02/06/06 | Bloomsburg PA - Nelson Field House | ESU 78, Bloomsburg 65 | Box score |
| 02/04/06 | Kutztown PA - Keystone Arena | Kutztown 76, ESU 73 | Box score |
| 02/01/06 | East Stroudsburg PA - Koehler Fieldhouse | ESU 87, Mansfield 69 | Box score |
| 01/30/06 | East Stroudsburg PA - Koehler Fieldhouse | ESU 90, PSU-Hazleton 66 | Box score |
| 01/28/06 | West Chester PA - Hollinger Field House | ESU 67, West Chester 58 | Box score |
| 01/25/06 | East Stroudsburg PA - Koehler Fieldhouse | ESU 75, Cheyney 71 | Box score |
| 01/21/06 | Millersville PA - Pucillo Gym | ESU 92, Millersville 76 | Box score |
| 01/15/06 | Clarion PA | Clarion 73, ESU 65 | Box score |
| 01/11/06 | East Stroudsburg PA - Koehler Fieldhouse | ESU 83, Bloomsburg 73 | Box score |
| 01/08/06 | East Stroudsburg PA - Koehler Fieldhouse | ESU 78, IUP 56 | Box score |
| 01/07/06 | East Stroudsburg PA - Koehler Fieldhouse | ESU 79, Lock Haven 66 | Box score |
| 01/03/06 | East Stroudsburg PA - Koehler Fieldhouse | ESU 112, Briarcliffe 49 | Box score |
| 12/21/05 | East Stroudsburg PA - Koehler Fieldhouse | California 82, ESU 77 | Box score |
| 12/20/05 | East Stroudsburg PA - Koehler Fieldhouse | Shippensburg 81, ESU 75 | Box score |
| 12/10/05 | East Stroudsburg PA - Koehler Fieldhouse | Pitt-Johnstown 70, ESU 64 | Box score |
| 12/09/05 | East Stroudsburg PA - Koehler Fieldhouse | ESU 97, PSU-Schuylkill 55 | Box score |
| 12/04/05 | Edinboro PA | Edinboro 77, ESU 69 | Box score |
| 12/03/05 | Slippery Rock PA - Morrow Field House | ESU 74, Slippery Rock 68 | Box score |
| 11/28/05 | Shippensburg PA - Heiges Field House | Shippensburg 58, ESU 45 | Box score |
| 11/19/05 | Elkins, WV - Memorial Gym | ESU 77, Davis & Elkins 71 | Box score |
| 11/22/05 | Caldwell NJ - George R. Newman Center | ESU 72, Caldwell 58 | Box score |
| 11/14/05 | East Stroudsburg PA - Koehler Fieldhouse | ESU 68, USP 60 | Box score |